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MAKOplasty®

Clinical Research at MAKO Surgical Corp. is multi-faceted.

Whether it is improving surgical accuracy, operating room efficiency, or patient outcomes, MAKO Surgical Corp. is committed to improving orthopedic surgery. MAKO has developed a joint registry with a goal of tracking the outcomes MAKO prostheses implanted.

In addition, we have focused studies aimed at quantifying the improvement in accuracy of implant placement, return to functional activities, preservation of bone stock, and in vivo knee kinematics measured fluoroscopically. Our studies have also measured the accuracy of cup placement in MAKOplasty® THA. All studies compare their results to the alternative treatment options that are currently available.

Our comprehensive research program provides evidence of the clinical and functional value of our robotic arm system for placement of corresponding implants, as well as laying a scientific foundation for the support and development of future products and applications.

MAKOplasty® Robotic Arm Accuracy

UKA

Robotic arm assisted UKA leads to component placement that is:
  • 2 to 3 times more accurate
  • at least 3 times more reproducible with fewer outliers

THA

Robotic arm assisted THA greater accuracy than manual THA in cadaveric acetabulae:

Average manual errors when compared to robotic arm assistance.

Robotic acetabular cup placement was 5.9 times more accurate for cup inclination and 4.0 times more accurate for cup version when compared to manual cup placement.

Pre- and Post-operative CT scans are used to demonstrate the accuracy of the MAKOplasty® procedure. In this cadaveric study, one acetabular cup was placed manually (right side of image) and one was placed with robotic-arm assistance (left side of image). The blue cup represents the pre-operative planned placement of the cup. The orange cup is then overlayed on this image to demonstrate the actual post-operative placement of the cup. The accuracy of the RIO® compared to a traditional manual technique is demonstrated by the close alignment of the pre- and post-op cup overlays.

Padgett DE, Thompson MT, Conditt MA, Horowitz S, Jones JA, Dunbar NJ, Banks SA. Accuracy of robotic arm assisted acetabular cup implantation. 6th Annual MIRA Congress, May 11-13, 2011, Athens, Greece.

Peer Reviewed Manuscripts

  • Robotic Systems in Orthopaedic Surgery
    Lang JE, Mannava S, Floyd AJ, Goddard MS, Smith BP, Mofidi A, Seyler T, Jinnah RH.
    Journal of Bone and Joint Surgery – British. October2011;93B(10):1296-9.

  • Robotic Guidance in Total Hip Arthroplasty: The Shape of Things to Come
    Dorr LD, Jones RE, Padgett DE, Pagnano M, Ranawat A, Trousdale RT.
    Orthopedics. September2011;34(9):652-5.

  • Robotic Assisted Total Hip Arthroplasty Using the MAKO Platform
    Dorr LD, Tarwala R.
    Curr Rev Musculoskelet Med. September2011;4(3):151-6.

  • Retrospective Analysis of Total Knee Arthroplasty Cases for Visual, Histological, and Clinical Eligibility of Unicompartmental Knee Arthroplasties
    Arno S, Maffei D, Walker PS, Schwarzkopf R, Desai P, Steiner GC.
    The Journal of Arthroplasty. 2011;26(8):1396-1403.

  • Comparison of Interface Stresses and Strains for Onlay and Inlay Unicompartmental Tibial Components
    Walker PS, Parakh DP, Chaudharry ME, Wei C.
    The Journal of Knee Surgery. 2011;24(2):109-115.

  • Effects of Tibial Slope Changes in the Stability of Fixed Bearing Medial Unicompartmental Knee Arthroplasty in Anterior Cruciate Ligament Deficient Knees The Knee
    July2011, [in press]

  • Three-dimensional A-mode Ultrasound Calibration and Registration for Robotic Orthopaedic Knee Surgery
    Mozes A, Chang T, Arata L, Zhao W.
    International Journal of Medical Robotics and Computer Assisted Surgery. 2010;6: 91-101.

  • Future Directions in Knee Replacement
    Walker PS, Yildirim G, Arno S, Heller Y.
    Proc Inst Mech Eng. 2010;224(H):391-414.

  • The Role of Navigation and Robotic Surgery in Hip Arthroscopy
    Logishetty K, Bedi A, Ranawat AS.
    Operative Techniques in Orthopaedics. 2010;20:255-63.

  • Robotic Arm-Assisted UKA Improved Tibial Component Alignment: A Pilot Study
    Lonner JH, John TK, Conditt MA.
    Clin Orthop Relat Res. July2009;468(1):141-6.

  • Robotic-Arm Assisted Unicompartmental Knee Arthroplasty
    Lonner JH.
    Seminars in Arthroplasty. 2009;20(1):15-22.

  • Arthroscopic Robotic-Arm Assisted Unicompartmental Knee Arthroplasty
    O’Loughlin PF, Pearle AD, Fyhrie DP, Long F.
    J Am Acad Orthop Surg. 2009;17. 266-269.

  • Minimally Invasive Robotic-Arm Guided Unicompartmental Knee Arthroplasty
    Conditt MA, Roche M.
    Journal of Bone and Joint Surgery. 2009;91(1):63-8.

  • Indications for Unicompartmental Knee Arthroplasty and Rational for Robotic-Arm Assisted Technology
    Lonner JH.
    American Journal of Orthopedics. 2009;XXXVIII(2S):3-6.

  • Integrating Robotic Technology Into the Operating Room
    Coon TM.
    American Journal of Orthopedics. 2009;XXXVIII(2S):7-9.

  • Robot-Assisted Unicompartmental Knee Arthroplasty
    Roche MW, O’Loughlin PF, Kendoff D, Musahl V, Pearle AD.
    American Journal of Orthopedics. 2009;XXXVIII(2S):10-15.

  • Perioperative Management of Unicompartmental Knee Arthroplasty Using the MAKO Robotic System (MAKOplasty)
    Pearle AD, Kendoff D, Stueber V, Musahl V, Repicci JA.
    American Journal of Orthopedics. 2009;XXXVIII(2S):16-19.

  • Outcomes of Robotically Assisted Unicompartmental Arthroplasty
    Sinah RK.
    American Journal of Orthopedics. 2009;XXXVIII(2S):20-22.

  • Haptic Robotics Enable a Systems Approach to Design of a Minimally Invasive Modular Knee Arthroplasty
    American Journal of Orthopedics. 2009;XXXVIII(2S):23-27.

  • Modular Bicompartmental Knee Arthroplasty with Robotic Arm Assistance
    Lonner JH.
    American Journal of Orthopedics. 2009;XXXVIII(2S):28-31.

  • Technology and Cost Effectiveness in Knee Arthroplasty: Computer Navigation and Robotics
    Swank ML, Alikire M, Conditt MA, Lonner JH.
    American Journal of Orthopedics. 2009;XXXVIII(2S):32-36.

  • The New Arthritic Patient and Arthroplasty Treatment Options
    Argenson JNA, Parratte S, Bertani A, Aubaniac JM, Lombardi AV, Berend KR, Adams, JB Lonner JH, Mahoney OM, Kinsey TL, John TK, Conditt MA.
    Journal of Bone and Joint Surgery. 2009;91A: 43-8.

  • Precision Surgery
    Dorr LD, Deshmane P.
    Orthopedics. 2009;32: 659.

  • Robot-Assisted Unicompartmental Knee Arthroplasty
    Pearle AD, O’Loughlin PF, Kendoff D.
    The Journal of Arthroplasty. December2008;25(2):230-7.

Posters

Learning Curve of Robotically Assisted UKA
Does Conversion of a UKA to a TKA Require Medial Augmentation (IMUKA 2009)

Robotic Arm Guided UKA is More Accurate than Manually Instrumented UKA
One Year Outcomes of Robotic Arm Guided UKA Does Less Medial Tibial Plateau Resection Make a Difference in UKA

White Papers

Surgeon Editorials

Book Chapters

Lonner, J. H.: Robotic Arm-Assisted Unicompartmental Arthroplasty. In Master Techniques in Orthopedic Surgery: Knee Arthroplasty. Edited by Lotke, P. A., and Lonner, J. H., Philadelphia, PA, Lippincott Williams & Wilkins, 2008.

Peer Reviewed Scientific Presentations / Posters

  • Two Year Outcomes of Robotically Guided UKA
    • 22nd Annual Congress of ISTA, October 22-24, 2009, Big Island, Hawaii
  • Early Clinical Outcomes of Modular Bicompartmental Arthroplasty
    • 22nd Annual Congress of ISTA, October 22-24, 2009, Big Island, Hawaii
  • Early Clinical Outcomes of Robotic-Assisted UKA Compared with Conventional Manual Onlay Components
    • 22nd Annual Congress of ISTA, October 22-24, 2009, Big Island, Hawaii
  • In Unicompartmental Knee Replacement More Accurate with Robotic Assistance?
    • 22nd Annual Congress of ISTA, October 22-24, 2009, Big Island, Hawaii
  • What You Plan is What You Get: Initial Experience Implanting Unicondylar Knees Using a Haptically Guided Robotic System
    • 20th Annual Congress of ISTA, October 4-8, 2007, Paris, France
  • Does Conversion of a UKA to a TKA Require Medial Augmentation?
    • 21st Annual Congress of ISTA, October 1-4, 2008, Seoul, Korea
    • International Meeting for Unicompartmental Knee Arthritis, February 4-6, 2009, Maastricht, Netherlands
    • Institution of Mechanical Engineers, April 30 – May 2, 2009, London, England
  • Learning Curve of Robotic UKA
    • International Meeting for Unicompartmental Knee Arthritis, February 4-6, 2009, Maastricht, Netherlands
    • Institution of Mechanical Engineers, April 30 – May 2, 2009, London, England
    • International Society for Computer Assisted Orthopedic Surgery, June 17-20, 2009, Boston, MA
    • 22nd Annual Congress of ISTA, October 22-24, 2009, Big Island, Hawaii
  • Minimal invasive robot assisted unicompartmental knee arthroplasty
    • 8th Annual Meeting of CAOS-International, June 4-7, 2008, Hong Kong
  • Robotically Assisted UKA is More Accurate than Manually Instrumented UKA
    • 21st Annual Congress of ISTA, October 1-4, 2008, Seoul, Korea
    • International Meeting for Unicompartmental Knee Arthritis, February 4-6, 2009, Maastricht, Netherlands
    • 55th Annual Meeting of the ORS, February 22-25, 2009, Las Vegas, Nevada
    • Institution of Mechanical Engineers, April 30 – May 2, 2009, London, England
    • International Society for Computer Assisted Orthopedic Surgery, June 17-20, 2009, Boston, MA
  • Does Less Medial Tibial Plateau Resection Make a Difference in UKA?
    • 21st Annual Congress of ISTA, October 1-4, 2008, Seoul, Korea
  • Early Clinical Success of Novel Tactile Guided UKA Technique
    • 21st Annual Congress of ISTA, October 1-4, 2008, Seoul, Korea
  • Accuracy of Robotically Assisted UKA
    • 21st Annual Congress of ISTA, October 1-4, 2008, Seoul, Korea
    • 76th Annual AAOS Meeting – Scientific Program February 25-28, 2009, Las Vegas, Nevada
  • One Year Outcomes of Robotically Guided UKA
    • 21st Annual Congress of ISTA, October 1-4, 2008, Seoul, Korea
    • 76th Annual AAOS Meeting – Scientific Program February 25-28, 2009, Las Vegas, Nevada
  • Robotically Guided UKA: Outcomes of Initial Series
    • International Meeting for Unicompartmental Knee Arthritis, February 4-6, 2009, Maastricht, Netherlands
    • 55th Annual Meeting of the ORS, February 22-25, 2009, Las Vegas, Nevada
    • Institution of Mechanical Engineers, April 30 – May 2, 2009, London, England
    • 7th Biennial ISAKOS Congress, April 5-9, 2009, Osaka, Japan
    • International Society for Computer Assisted Orthopedic Surgery, June 17-20, 2009, Boston, MA
  • Unicompartmental Arthroplasty Using a Tactile Guidance System
    • 21st Annual Congress of ISTA, October 1-4, 2008, Seoul, Korea
  • Robotic Arm-Assisted Unicompartmental Knee Arthroplasty
    • International Society for Computer Assisted Orthopedic Surgery, June 17-20, 2009, Boston, MA

 

Related Links

Biomedical and life sciences journal literature
http://pubmed.gov/

Data on file.

Over 65 on-going studies in the following categories:

  • • Accuracy
  • • Clinical/Radiographic Outcomes
  • • Functional/Kinematic Outcomes
  • • Implant Design/Product Development
  • • Surgical Technique/Robotic Arm Use/Indications
  • • Healthcare Economics
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