Defining the
Market
Knee pain resulting from osteoarthritis (OA) is a vast and rapidly growing disease
expected to create considerable demand for knee arthroplasty in the near-term as the
US population ages and obesity rates rise.
• 15 Million Americans suffer with OA of the knee1
• OA is the most common form of arthritis
• OA is a leading cause of disability worldwide
The Population is Aging
As the population ages, the number of people aged
55+ (peak pain candidates) will grow three times
the average rate of the U.S. population reaching
96 Million by 2020.
Obesity Rates are Rising
Knee arthroplasty procedures doubled each decade and
obesity rates continue to rise. In 2000, 31% of the
adult U.S. population had a Body Mass Index (BMI)
of 30. This is estimated to rise to 40% by 2010.
The MAKOplasty®
Opportunity
MAKOplasty® brings new capabilities and more treatment options to serve the unmet
needs of patients suffering from early to mid-stage knee OA. The revolutionary robotic
arm technology and innovative tissue-sparing, multicompartmental implants are designed
together to result in a more natural feeling knee, a less invasive surgical option, and to
promote a quicker recovery.
References:
1 American Association of Orthopaedic Surgeons (2008). AAOS.org.
2 Duncan R, Hay E, Saklatvala J, Croft P. (2006). Prevalence of radiographic osteoarthritis: it all depends on your point of view. Rheumatology (45),
757-60.
3 Duke University Center for Demographic Studies (January, 2006). Assessing the impact of medical technology innovations on human capital.
Phase I Final Report (Part C): Effects of Advanced Medical Technologies – Musculoskeletal Diseases Medical Technology Assessment Working
Group: Prepared for the Institute for Medical Technology Innovation.
4 Ledingham J., Regan M., Jones A., & Doherty M. (1993). Radiographic patterns and associations of osteoarthritis of the knee in patients referred to
hospital. Annals of the Rheumatic Diseases (52), 520-526.
5 Rolston L., Sprague J., Tsai S., & Salehi A. (2006). A novel bone/ligament sparing prosthesis for the treatment of patellofemoral and medial
compartment osteoarthritis.AAOS 2006 Annual Meeting, Poster #P181.
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"I’ve been exposed to a lot of novel technologies …and I can honestly say, of them all, the MAKO system at this point seems to be the one that has the most impact on patient care."
Andrew Pearle, M.D. |
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Study survey reports 92% of men and 88% of
women decline implant surgery.
A Duke University study survey
reports that of those men and women whose physicians
recommended a total hip or knee replacement, a staggering 92
and 88 percent, respectively, did not take advantage of these
surgical procedures, despite their safety, success rates and
long-term positive outcomes. Fear of pain or worsened mobility,
misperception of advances in the rehabilitation process, and
lack of awareness of the full range of benefits afforded by
such interventions is behind the high patient refusal rates,
the study’s
investigators surmised3. |
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